January 12, 2022

Royals  sign Arodys Vizcaino

January 23, 2022

Royals  sign Colten Brewer

March 07, 2022

Royals  sign Brad Peacock

March 10, 2022

Royals  sign Daniel Mengden

March 16, 2022

Royals  place Amir Garrett on the injured list

Royals  place Tyler Zuber on the injured list

Royals  sign Zack Greinke as a free agent

April 21, 2022

Royals  place Ronald Bolanos on the injured list

April 24, 2022

Royals  designate Domingo Tapia for assignment

Matt Peacock traded from Diamondbacks  to Royals 

April 28, 2022

Royals  place Adalberto Mondesi on the injured list

April 30, 2022

Royals  place Jake Brentz on the injured list

May 02, 2022

Royals  place Cam Gallagher on the injured list

May 04, 2022

Royals  place Carlos Santana on the injured list

May 09, 2022

Royals  place Edward Olivares on the injured list

May 17, 2022

Royals  place Salvador Perez on the injured list

May 19, 2022

Royals  place Michael Taylor on the injured list

May 26, 2022

Royals  place Amir Garrett on the injured list

Royals  place Kyle Isbel on the injured list

May 30, 2022

Royals  place Matt Peacock on the injured list

Royals  place Gabe Speier on the injured list

Royals  place Zack Greinke on the injured list

June 03, 2022

Royals  designate Dairon Blanco for assignment

Albert Abreu traded from Rangers  to Royals 

June 13, 2022

Royals  place Joel Payamps on the injured list

June 17, 2022

Royals  designate Albert Abreu for assignment

June 24, 2022

Royals  place Daniel Lynch on the injured list

Royals  place Salvador Perez on the injured list

June 26, 2022

Royals  place Josh Staumont on the injured list

June 27, 2022

Royals  designate Ronald Bolanos for assignment

July 01, 2022

Royals  designate Matt Peacock for assignment

July 10, 2022

Royals  place Jon Heasley on the injured list

July 11, 2022

Royals  designate Foster Griffin for assignment

Drew Waters traded from Braves  to Royals 

July 16, 2022

Foster Griffin traded from Royals  to Blue Jays 

July 18, 2022

Royals  place Daniel Lynch on the injured list

July 22, 2022

Royals  place Edward Olivares on the injured list

July 27, 2022

Royals  place Angel Zerpa on the injured list

Andrew Benintendi traded from Royals  to Yankees 

August 01, 2022

Anthony Misiewicz traded from Mariners  to Royals 

August 02, 2022

August 09, 2022

Royals  place Taylor Clarke on the injured list

August 18, 2022

Royals  designate Joel Payamps for assignment

August 23, 2022

Royals  place Vinnie Pasquantino on the injured list

August 24, 2022

Royals  place Zack Greinke on the injured list

Royals  place Josh Staumont on the injured list

Royals  sign Jakson Reetz

September 02, 2022

Royals  designate Daniel Mengden for assignment

October 04, 2022

Royals  place Taylor Clarke on the injured list

November 06, 2022

Zack Greinke became a free agent

November 10, 2022

Royals  designate Sebastian Rivero for assignment

November 15, 2022

Royals  designate Jake Brentz for assignment

Royals  designate Brent Rooker for assignment

November 16, 2022

Royals  release Sebastian Rivero

November 18, 2022

Jake Brentz became a free agent